At-Home PGX Testing Options

Our psychiatric pharmacogenomics (PGx) test provides essential information on 9 genes which may affect metabolism and response to 125+ drugs often used in the treatment of mental health disorders. Clinicians can use the personalized information provided with this PGx test to help select the best medication and dose for an individual patient, limiting potential adverse drug reactions.

Drug Metabolism Genotyping
Also known as pharmacokinetics, this analysis predicts the body’s impact on a drug. Its purpose is to determine patient-specific genetic variants that may influence the function of drug-metabolizing enzymes. It shows whether a patient is an ultrarapid metabolizer, extensive metabolizer, intermediate metabolizer, or poor metabolizer of a medication. Understanding your metabolizer phenotype is important, as it indicates how much of a drug may be active in the body to produce either therapeutic or toxic effects.

Drug Response Genotyping
Also known as pharmacodynamics, this analysis describes a drug’s predictive impact on the body. It considers the likelihood of a drug producing the desired therapeutic effect by identifying patient-specific genetic variants involved in how medications work. This can indicate the likelihood of a good (therapeutic) or bad (adverse) drug response.

You’ll receive everything you need in order to self-collect your test specimen!

• Pre-paid shipping both ways
• Easy to follow instructions
• An at-home DNA collection kit (via an easy cheek swab)
• Return protective envelope to mail sample to the lab for testing
• Electronic passcode protected results available from your phone or computer
• Free telehealth result explanation
• Printable report to share with your doctor
• Help along the way if you need it

4U Health’s Comprehensive Medication Response Test informs you on the usefulness of 224 medications in the following categories: anti-cancer, cardiovascular, diabetes, gastrointestinal, infectious disease, pain management, psychiatry, rheumatology, transplantation, and urology.

Discover how your body is likely to metabolize this extensive list of drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

4U Health’s Psychiatric Medication Response Test informs you on the usefulness of 125+ medications mainly used in mental health treatment, including but not limited to: Antiaddictives, Anti-ADHD Agents, Anticonvulsants, Antidepressants, Antipsychotics, Benzodiazepines, and other Neurological Agents.

Discover how your body is likely to metabolize this extensive list of drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

4U Health’s Cardiac Medication Response Test informs you on the usefulness of 40+ medications mainly used to help improve cardiovascular health, including Angiotensin II Receptor Antagonists, Antianginal Agents, Antiarrhythmics, Anticoagulants, Antiplatelets, Beta Blockers, Diuretics, and Statins.

Discover how your body is likely to metabolize this extensive list of cardiac drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

4U Health’s Pain Medication Response Test informs you on the usefulness of 40 medications in the following categories: Fibromyalgia Agents, Muscle Relaxants, NSAIDs, Opioids, Anti-Hyperuricemics, Anti-gout Agents, and Immunomodulators.

Discover how your body is likely to metabolize this extensive list of drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

Clinicians prescribe medications to treat disease or alleviate symptoms. The last thing you might expect is that a prescribed medication may do more harm than good. An adverse drug reaction (ADR) refers to the unintended side effects of a prescribed medication. A drug-induced disease occurs when an ADR warrants a patient consulting a doctor or getting hospitalized.

ADRs and drug-induced diseases are a reality. FDA studies estimate that 7% of hospitalized patients have a severe adverse drug reaction.² Drugs are approved by the FDA for use only if their potential benefits far outweigh the risks involved. But it’s important to note not all people react similarly to a drug. A particular medicine may benefit some people while causing others potentially life-threatening unintended side effects.

A drug response test like this alerts patients and guides clinicians through the practice of personalized medicine. It allows prescribers to empirically select the best medications based on a patient’s unique genetic traits. This test may increase the likelihood of an optimal therapeutic outcome and limit the chances of an adverse drug reaction.

One of the transformative trends in medicine is personalized pharmacy therapy. With the advent of medication response PGx tests, physicians and pharmacists alike can individualize a patient’s drug therapy consistent with that patient’s unique genetic makeup.

Our Psychiatric Medication Response (PGx Gene Test) provides personalized medication guidance on 125+ medications mainly used in mental health treatment, including but not limited to: Antiaddictives, Anti-ADHD Agents, Anticonvulsants, Antidepressants, Antipsychotics, Benzodiazepines, and other Neurological Agents.

This state-of-the-art genetic test includes at no additional charge result explanation by a healthcare professional to help you better understand your medication response report. We’ll give you the information necessary to have an informed discussion with your physicians and pharmacists to get the most out of your results.

This is our most complete medication response test and analyzes 20 genes to identify 244 medications for potential genetic induced adverse drug reactions.

Analyzes 20 Genes:
ANKK1, DRD2, Apolipoprotein E, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, F2, F5, ITGB3, LPA, MTHFR, OPRM, SLCO1B1, TPMT, and VKORC1.

See Full List of Genes and Alleles Tested

This test provides an analysis of 9 genes to identify 125+ medications often used in mental health treatment for potential genetic induced adverse drug reactions.

Analyzes 9 Genes:
ANKK1, DRD2, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2D6, MTHFR, OPRM1.

See Full List of Genes and Alleles Tested

This test provides an analysis of 13 genes to identify 40+ medications often used to help improve cardiovascular health for potential genetic induced adverse drug reactions.

Analyzes 13 Genes:
Apolipoprotein E, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, Factor II, Factor V Leiden, ITGB3, LPA, MTHFR, SLCO1B1, and VKORC1.

See Full List of Genes and Alleles Tested

This test provides an analysis of 8 genes to identify 40 medications often used in pain management for potential genetic induced adverse drug reactions.

Analyzes 8 Genes:
COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, OPRM, and TPMT.

See Full List of Genes and Alleles Tested

Multiple factors influence how a person reacts to a drug including:

• Genetics
• Age
• Allergies
• Medical History
• Weight and Body Size

The Psychiatric Medication Response (PGx Gene Test) is not suitable for the following groups of people:

• Children under 2-years-old
• Specimens collected in New York State

If you’re experiencing a severe adverse drug reaction, such as difficulty breathing, vision problems, hives, fever, or vomiting, we recommend you speak with your healthcare provider right away.

Test now or within one year of purchase. This kit has a guaranteed expiration date of at least 12 months. That’s great news if you are buying now but want to test yourself in the future or gifting to a friend or family member for later use.

4U Health tests meet national standards and are as accurate as services provided in a doctor’s office or hospital. We only work with the highest quality CLIA certified laboratories and health experts. All testing complies with state and federal regulations. And our clinicians provide medical oversight throughout the entire process.

All 4U Health tests are eligible for gifting. In fact, they make great presents. The recipient who receives your gift will simply open the kit, register it, and follow the collection instructions. Within a few days of sending to the lab, your friend or family member will receive secure electronic HIPAA compliant results all thanks to your generosity.

Many physicians don’t routinely order a medication response PGx Gene test. That’s because DNA tests like this often require pre-authorization from insurance carriers. If denied, patients with insurance coverage may face unexpected medical bills often in excess of a thousand dollars.

With 4U Health you pay a fair price upfront and receive no surprise medical bills. 4U Health is not enrolled in Medicare or any other private insurance network. This test is not eligible for Medicare or any other federal or state-funded insurance program reimbursement.

So you still have unanswered questions. No worries, we’d love to hear from you. Reach us by e-mail, phone or chat and we will do our best to provide answers so you can determine if this is the best test for you or your child.

• 866-610-1200
• help@4uhealth.com
• Chat Support 
   
• PO Box 100083
  Pittsburgh, PA 15233

Rest assured; HIPAA security standards protect your data every step of the way while determining your gene to drug responses. Keeping your confidential data secure is our number one priority. We only share your information when required to deliver our products and services or where we are legally obligated to do so. Your results are securely protected and available for review in your online portal; always secure but easily accessible only to you.